Radically improving cancer diagnostics

Our technology, superRCA, can detect 1 mutation in 100 000 wild-types

Rarity superRCA technology
superRCA published in Nature Communications
Raritys teknik är 10 till 100 gånger mer känslig än dagens teknik
Rarity support Elicera Therapeutics in cutting edge CAR-T therapy study

Rarity superRCA is an ultrasensitive multiplex assay for detecting rare nucleic acid sequences in biological samples like liquid biopsies. The format and flexibility of the technology platform – and read-out based on flow cytometry – makes it suitable for research as well as clinical application.

Detect down to 1 mutation in 100 000 wild types. Because sensitivity matters.

Our services

Doctor applying tourniquet on patient's hand for taking blood sample from vein in hospital

Clinicians

Fast, reliable and ultrasensitive decision-making tools for improved cancer care.

Rarity Biosciences’ vision is to democratize cancer diagnostics by providing more accessible, patient-near laboratory analysis – based on a simple blood sample.

An ultrasensitive liquid biopsy assay can be analysed for all relevant mutations along with other blood works on existing instruments, in a laboratory near the practicing clinician.

superRCA is an ultra-sensitive and specific molecular amplification technology. It is used to detect very small amounts of DNA sequence variants, like cancer mutations, in patient tissue and blood samples.

Scientist or researcher or phd student put dna samples into pcr for analysis in a biotechnology laboratory

Laboratories

Patient-near laboratory testing and read-out on established flow cytometry.

Rarity superRCA can expand the services of most hematology labs by providing highly-accurate, specialist cancer diagnostics, based on a simple blood test.

The Rarity superRCA assays are not only ultra-sensitive and multiplex, but fast and cost-efficient because they can be performed in a laboratory close to the treating clinician – on unused capacity of existing laboratory instrumentation.

Talk to us about partnering for patient-near specialist diagnostics and find out how you can expand your service offering without heavy investment.

lab

Researchers

RUO kits and discovery panels for detecting rare nucleic acid sequences.

Rarity superRCA ultra-sensitive RUO kits allow you to detect and quantify extremely low amounts of nucleic acid sequences in tissue or blood samples.

We offer Ready-to-use RUO kits for AML, including probes, primers and preoptimized reagents, Designed RUO kits for targeted sequences for biomarker discovery at custom request and Collaboration and partnering at request.

Collaborate with us for clinical validation studies in AML, and to identify other clinical applications as well as for research and pharmaceutical development.

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Application: Rarity superRCA assay detects AML mutations

A recent discovery study on a cohort of 52 patients showed that Rarity superRCA is able to detect four of the most common mutations in Acute myeloid leukemia (AML) with a greater sensitivity than current test practice i.e. ddPCR and NGS. In addition, a study of multiple follow-up samples from three of the patients, showed that relapse could have been detected in one of the patients as much as three months earlier. The studies were carried out in collaboration with Associate Prof. Lucia Cavelier from the Uppsala University Hospital.

Encouraged by these initial results, we are looking for partnering research centers and collaborations in clinical studies.

Contact us for more information.

Rarity SuperRCA technology

Ultrasensitive and reliable

10-100 times more sensitive than current technology. Detects 1 mutation in 100 000

Multiplex but simple

Run tests on up to multiple targets simultaneously. Analyze by established flow cytometry

Fast & cost-efficient

Patient-near testing on existing equipment for fast results and better patient outcomes

Democratizing cancer diagnostics for better patient outcomes

Rarity Biosciences’ vision is to democratize cancer diagnostics by providing more accessible, patient-near laboratory analysis – based on a simple blood sample. An ultrasensitive liquid biopsy assay that can be analysed for all relevant mutations along with other blood works, in a lab near the practicing clinician.

Contact us

Partnering

We are currently looking for collaboration and partners in clinical research and biopharmaceutical development that are interested in using our technology platform as a research tool for the development of new biomarker signatures and companion diagnostics.

Contact us, if you are interested in partnering with us for clinical trials – or if you are interested in using superRCA in your research or for pharma development.

Partnering