Radically improved mutation detection
Empowering confident decisions
Rarity Bioscience’s proprietary superRCA® technology delivers unmatched sensitivity for detecting low-frequency mutations, improving measurable residual disease assessment while enabling deeper insights into disease biology.
Radically improved mutation detection
Empowering confident decisions
Rarity Bioscience’s proprietary superRCA® technology delivers unmatched sensitivity for detecting low-frequency mutations, improving measurable residual disease assessment while enabling deeper insights into disease biology.
At Rarity Bioscience
Decentralizing ultra-sensitive mutation detection
We develop ultra-sensitive mutations assays designed to run on available instruments and standard flow-cytometers.
We push the boundaries of science with one shared mission:
we enable tomorrow's precision medicine, today.
we enable tomorrow's precision medicine, today.
At Rarity Bioscience
Decentralizing ultra-sensitive mutation detection
We develop ultra-sensitive mutations assays designed to run on available instruments and standard flow-cytometers.
We push the boundaries of science with one shared mission:
we enable tomorrow's precision medicine, today.
we enable tomorrow's precision medicine, today.
Research use only (RUO)
The challenge:
The limits of conventional detection
In this space, you are searching for mutations that should not exist — measuring against a baseline of zero.
Detecting such rare signals demands ultra-sensitive technologies capable of identifying a single malignant cell among hundreds of thousands, or even millions. Enabling new and improved research applications.
Detecting such rare signals demands ultra-sensitive technologies capable of identifying a single malignant cell among hundreds of thousands, or even millions. Enabling new and improved research applications.
In this space, you are searching for mutations that should not exist — measuring against a baseline of zero. Detecting such rare signals demands ultra-sensitive technologies capable of identifying a single malignant cell among hundreds of thousands, or even millions. Enabling new and improved research applications.
Technology enables:
✓ Mutant variant screening
✓ Residual mutations detection
✓ Relapse detection
✓ Resistance Marker
✓ Therapy response research
✓ Drug development
Research use only (RUO)
Transforming
mutation detection
Because sensitivity matters
superRCA is a patented dual-RCA technology that amplifies single mutated DNA molecules into large, fluorescent particles. This enables quantifiable detection of mutations with a sensitivity of 1:100,000 — up to 100× more sensitive than conventional methods.
Transforming mutation detection
Transforming
mutation detection
Because sensitivity matters
superRCA is a patented dual-RCA technology that amplifies single mutated DNA molecules into large, fluorescent particles.
This enables quantifiable detection of mutations with a sensitivity of 1:100,000 — up to 100× more sensitive than conventional methods.
This enables quantifiable detection of mutations with a sensitivity of 1:100,000 — up to 100× more sensitive than conventional methods.
superRCA is a patented dual-RCA technology that amplifies single mutated DNA molecules into large, fluorescent particles. This enables quantifiable detection of mutations with a sensitivity of 1:100,000 — up to 100× more sensitive than conventional methods.
Up to 100‑fold higher sensitivity,
powered by three core factors
Up to 100‑fold higher sensitivity, powered by three core factors
High DNA input
Sensitivity follows the math: your limit of detection is directly determined by the amount of material available. More input means deeper insight.
Multifactor genotyping
A robust error‑correction strategy that eliminates false signals and delivers exceptionally low background noise.
High event counts
Measuring a large number of molecular events increases precision and ensures reliable data even at ultra‑low variant levels.
Innovation without investment
Seamlessly fits into your lab workflow
superRCA assays are simple to run, whether manually or fully automated, using standard laboratory equipment or widely available automation platforms.
Detection is performed on conventional flow cytometers, a technology with over 75,000 instruments installed globally, ensuring broad accessibility and seamless integration into existing lab workflows without the need for any larger investments.
Detection is performed on conventional flow cytometers, a technology with over 75,000 instruments installed globally, ensuring broad accessibility and seamless integration into existing lab workflows without the need for any larger investments.
Scientifically validated
by leading researchers
Leading researchers spanning a multitude of disciplines have evaluated and implemented our mutation detection platform, resulting in numerous peer-reviewed publications. Through these independent studies, the technology has consistently demonstrated strong analytical performance and high sensitivity.
This continuously growing body of evidence represents a real‑world confirmation from respected experts and their findings reinforce the potential of the platform and highlight its value for applications where sensitivity truly matters.
This continuously growing body of evidence represents a real‑world confirmation from respected experts and their findings reinforce the potential of the platform and highlight its value for applications where sensitivity truly matters.
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