1 mutation in 100 000 wild-types because sensitivity matters

Radically improving cancer diagnostics

Rarity superRCA is an ultrasensitive multiplex assay for detecting rare nucleic acid sequences in biological samples like liquid biopsies. The format and flexibility of the technology platform – and read-out based on flow cytometry – makes it suitable for research as well as clinical application.

Enabling full potential of liquid biopsies

Rarity offers ultrasensitive superRCA® assays for research, available for service testing. The superRCA® assays are designed for extreme sensitivity to enable the full potential of liquid biopsy.

available assays

0 +

multiplexitivity

0 ,5 h

turnaround time

1: 0

sensitivity

What is superRCA®?

superRCA is an ultra-sensitive and highly specific molecular amplification technology. It is used to detect very small amounts of DNA sequence variants, like cancer mutations, in patient tissue or Liquid Biopsies.

It offers effective detection of multiple targets simultaneously – so called multiplexing. The assay can be performed in most hematology laboratories with existing equipment, using well-established flow cytometry for read-out, enabling more accessible testing with shorter response times.

About us

Rarity Biosciences was founded in 2021 as a spin out from Uppsala University to further develop and commercialize the superRCA assay technology. The superRCA technology was first discovered and developed by PhD Lei Chen and Professor Ulf Landegren in the Molecular Tools group at the Department of Immunology, Genetics, and Pathology.

Want to know more about our history of research and our different methods?

2023 Munich AML conference poster_Rarity_cut

MRD poster presented at international AML conference

20 mars, 2023

CEO Linus Bosaeus and co-founder and CTO Dr. Lei Chen attended the AML Conference in Munich, Germany 2023, to engage

Open position at Rarity Bioscience

8 mars, 2023

We are aiming at radically improving cancer diagnostic and are expanding our Research and Development team, we need you as

New assay available in our product portfolio

1 mars, 2023

Using the superRCA technology, you can essentially detect any known sequence of interest using target specific ligation templates and padlock

Ultrasensitive and reliable

10-100 times more sensitive than current technologies, detecting down 1 mutation in 100,000

Multiplex but simple

Analyse on up to 100 targets from the same DNA sample, with uncompromised sensitivity using the superRCA multiplex

Fast & cost-efficient

Read-out using flow cytometry enables patient-near testing on existing equipment for fast and cost-efficient testing

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