Products and Services

ASSAYS FOR ultra-sensitive
MUTATION DETECTION

Advancing molecular diagnostics through a technology that is redefining how low‑frequency mutations are being detected. Using equipment that is already readily available in most laboratories.

Product images

superRCA is an ultra-sensitive assay platform enabling ultra‑sensitive mutation detection with straightforward readout on standard flow cytometers. The superRCA Accessory Kit provides all shared assay components, while the superRCA Mutation Kit supplies the mutation‑specific probe required for each target.

The flexible superRCA platform

superRCA is an ultra-sensitive assay platform enabling ultra‑sensitive mutation detection with straightforward readout on standard flow cytometers. The superRCA Accessory Kit provides all shared assay components, while the superRCA Mutation Kit supplies the mutation‑specific probe required for each target.

superRCA®
Our platform concept

platform concept superRCA Mobile

superRCA®
Our platform concept

01
Flow cytometry

The superRCA platform offers read-out on most commercially avaliable flow cytometer platforms.

02
Accessory kit

The Accessory kit contains mutation agnostic coponent that enables the flow cytometer read-out.

03
Mutation kits

Mutation kits are extensively validated and available from stock, while on-demand kits cover 200+ mutations and are made to order.

MUTATION KITS

superRCA Mutation RUO

Mutation
LoB
LoQ
LoD
Disease Area
NPM1
<0.001%
0.005%
0.005%
AML NPM1 Chart
superRCA NPM1 Mutation Kit RUO
LoB: <0.001%
LoQ: 0.005%
LoD: 0.005%
Available sizes:
Art. No. 30-0001
Sample Type: Purified DNA
Recommended DNA input: 660ng
Disease area: Hematology
KIT D816V
0.0003%
0.0042%
0.00016%
superRCA KIT D816V Mutation Kit RUO
LoB: 0.0003%
LoQ: 0.0042%
LoD: 0.00016%
Available sizes:
Art. No. 30-0002
Sample Type: Purified DNA
Recommended DNA input: 660ng
Disease area: Hematology
JAK2 V617F
0.0012%
0.0037%
0.0037%
superRCA JAK2 V617F Mutation Kit RUO
LoB: 0.0012%
LoQ: 0.0037%
LoD: 0.0037%
Available sizes:
Art. No. 30-0004
Sample Type: Purified DNA
Recommended DNA input: 660ng
Disease area: Hematology

LoB - Limit of Blank, LoQ - Limit of Quantitation, LoD - Limit of Detection

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On-demand Mutation Assays

We have a broad library of on-demand products. Search for your gene mutations below and get in touch with one of our experts. We are happy to help you get the most out of your samples with the superRCA technology!

Browse On-demand assay catalog

Search in the field below to find your gene mutation.

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ACCESSORIES

Enabling components for the superRCA platform

Accessory Kit
superRCA Accessory Kit RUO
superRCA Accessory Kit RUO
The superRCA Accessory Kit RUO contains all the necessary enzymes and buffers to support the generation of superRCA particles, but does not generate any results on its own. It is compatible with all superRCA Mutation Kits RUO.

This product is for research use only (RUO) and is not intended for use
Art. No. 20-0001
Size: 200 reactions
Dilution Buffer
superRCA Dilution Buffer RUO
The superRCA Dilution Buffer should be used when there is a need to increase the total reaction volume, as when running in tubes or under certain instrument conditions.

The provided amount is sufficient to expand the volume of 900 reactions to be acquired in plate format, or 250 reactions to be acquired in tube format.
Art. No. 10-0001
Size: 45ml
Plate Insert
superRCA Plate Insert A RUO
The plate insert is used to stabilize the 96-well plates during read-out on Bekton Dickinson FACSLyric instruments.
Art. No. 20-0002
Size: 1 plate
Custom superRCA assays

Custom assay design

Assays designed around your exact sequence

If you do not find the sequence you need, our team can design a custom assay for you. Private mutation assays and custom sequence assays are available as custom design kits and are delivered pre‑verified for seamless use with the superRCA Accessory Kit. Assays can be supplied as single targets or multiplexed combinations.

Custom assays can be developed for most genomic variants, including single‑nucleotide variants, insertions, and deletions, ensuring broad compatibility with diverse clinical and research applications.

Sample analysis services

Experience superRCA before implementation

Not ready to bring superRCA in-house just yet? Send us your samples and let our team do the work.

Our laboratory analysis service gives you direct access to the superRCA ultra-sensitive mutation detection platform, run by our experienced staff, using validated workflows optimized and run in our ISO 13485 certified laboratory. You will receive reliable, high-quality data without needing to invest time and money in instrumentation and training.

This could be an ideal step if you are looking to evaluate the technology, prior to committing to a full implementation at your institution.

For research use only (RUO), not intended for use in diagnostic procedures.

Experience superRCA

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Product Data Sheet Accessory Kit EN V1

Mutation Details

Panel

Assay Name

Insert value

Gene Name

Insert value

Gene Symbol

Insert value

Serial Number

Insert value

COSMIC ID

Insert value

Amino Acid Change

Insert value

cDNA Mutation

Insert value

dbSNP

Insert value

Transcript

Insert value

Position_hg38

Insert value

CHR-hg38

Insert value

DNA input

Insert value

REF

Insert value

ALT

Insert value

Regulatory Status

Insert value

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superRCA JAK2 V617F Mutation Kit RUO

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Product Data Sheet superRCA JAK2 V617F Mutation Kit RUO
Datasheet specification superRCA KIT D816V Mutation Kit RUO

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superRCA KIT D816V Mutation Kit

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superRCA NPM1 Mutation Kit RUO

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Mutation Details

Panel

Assay Name

Insert value

Gene Name

Insert value

Gene Symbol

Insert value

Serial Number

Insert value

COSMIC ID

Insert value

Amino Acid Change

Insert value

cDNA Mutation

Insert value

dbSNP

Insert value

Transcript

Insert value

Position_hg38

Insert value

CHR-hg38

Insert value

DNA input

Insert value

REF

Insert value

ALT

Insert value

Regulatory Status

Insert value

Datasheet Specification superRCA NPM1 Mutation Kit RUO

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