Rarity offers ultrasensitive superRCA® assays for research, available for service testing. The superRCA® assays are designed for extreme sensitivity to enable the full potential of liquid biopsy.
Unique features:
- Parallel target analysis using same sample. Due to the unique superRCA technology, multiple mutations can be analyzed using the same sample.
- Multiplex setup for high cost efficient and high throughput analysis
- Extreme sensitivity, for most mutations in the range of 1:100,000
- High detection efficiency to optimize sensitivity for low sample input
- High GC mutations can be analyzed with unparallel precision, such as ASXL1 and SRSF2
- Dynamic range to manage sample volumes from 5ng up to 1320ng
- Handles most types of DNA input, such as cfDNA from plasma, genomic DNA from tumors or white blood cells
- Internal quality controls ensures accurate and reliable data, always
Gene-specific tests
Below is a list of available genes and mutation targets for service testing. The assay can in principal be setup to detect any mutation with a known sequence. Contact us for additional mutations or multiplex setup for high throughput
Mutations
Sample input
Genomic DNA, cfDNA (plasma)
Input range
5ng up to 1320ng
Regulatory status
Research use only
Panel
IDH1/2 Panel
Mutations
Sample input
Genomic DNA, cfDNA (plasma)
Input range
5ng up to 1320ng
Regulatory status
Research use only
Panel
IDH1/2 Panel
Mutations
Sample input
Genomic DNA, cfDNA (plasma)
Input range
5ng up to 1320ng
Regulatory status
Research use only
Mutations
Sample input
Genomic DNA, cfDNA (plasma)
Input range
5ng up to 1320ng
Regulatory status
Research use only
Panel
SRSF2 Panel
Mutations
Sample input
Genomic DNA, cfDNA (plasma)
Input range
5ng up to 330ng
Regulatory status
Research use only
Panel
Lung Cancer Panel
Mutations
Sample input
Genomic DNA, cfDNA (plasma)
Input range
5ng up to 330ng
Regulatory status
Research use only
Panel
Lung Cancer Panel
Target: CAR based Sequence
Example data from custom sequence assay
Sample input
Genomic DNA
Input range
5ng up to 1320ng
Regulatory status
Research use only
