Rarity Bioscience’s Linus Bosaeus and Lei Chen were at the CYTO 2024 Conference in Edinburgh, to present the study Ultra-sensitive Molecular MRD on Flow Cytometer using superRCA Mutation Assay, showcasing our new ultra-sensitive mutation detection technology superRCA.
- Title: Ultra-sensitive Molecular MRD on Flow Cytometer using superRCA Mutation Assay
- The presentation showcases Rarity Bioscience's game-changing approach to detecting minimal residual disease (MRD) through the utilization of the ultra-sensitive superRCA mutation assay.
Advancing Precision Medicine
In addition to showcasing the new ultra-sensitive mutation detection technology superRCA, our participation in CYTO 2024 underscores Rarity Bioscience’s dedication to advancing precision medicine. The superRCA technology enables identification of rare tumor-specific mutations, even at low frequencies, with high specificity and ultra-high sensitivity. We believe this has the potential to revolutionize the monitoring and treatment landscape for diseases like acute myeloid leukemia (AML), Myelodysplastic syndromes (MDS) and solid tumours.
Presentation at CYTO 2024
While there was a lot of focus on the new nano flow instruments for analysis of extracellular vesicles, as well as updates on the menus of spectral flow, the most novel application came from Rarity Bioscience’s Lei Chen in the presentation on detection of nucleic acid using regular flow cytometry. Attendees were enlightened about the revolutionary superRCA technology, marveling at its precision in detecting genetic mutations at ultra-low levels.
A strand of DNA is only 2,5nm in size, and practically undetectable, but the superRCA assays convert tiny DNA fragments into flow detectable particles. While still almost invisible on regular scatter parameters, the superRCA particles are extremely fluorescent and easy to gate and enumerate with extreme accuracy.
It was undeniably a presentation that left a lasting impact, one not to be missed!
If you want to learn more about the superRCA technology, go to our technology page:
Thanks CYTO 2024 for a fantastic conference!


