1 mutation in 100 000 wild-types
because sensitivity matters
Applications
Rarity superRCA® is an ultrasensitive multiplex assay for detecting rare nucleic acid sequences in liquid biopsy or tissue samples.
1 mutation in 100 000 wild-types
because sensitivity matters
Rarity superRCA® is an ultrasensitive multiplex assay for detecting rare nucleic acid sequences in liquid biopsy or tissue samples.
Greater knowledge of MRD and post-treatment disease surveillance offers the promise of improved treatment and resistance monitoring, as well as better risk stratification. However, research has been limited by low sensitivity and impractical turn-around times for sampling and analysis.
The superRCA® assays offer ultra-high sensitivity for detecting singe or of multiple mutation targets simultaneously, in a panel or individually, for advanced translational research.
Rarity Bioscience’s superRCA® assays offer the ultra-high sensitivity detection of multiple mutation targets simultaneously needed to analyze genomic and cell-free DNA in liquid biopsies.
The utilization of very short nucleic acid detection sequences in the superRCA assay also gives good performance in liquid biopsies prone to nucleosome fragmentation.
Mutation analysis using genomic and cell-free DNA in solid and liquid biopsies has become an integral part of biomarker assessment in drug development and clinical trials. It can also be used to better define inclusion criteria in clinical studies and patient stratification to treatment groups, and aid in monitoring of progression.
The easy-to-use superRCA® assay technology uses standard flow cytometers for sample analysis that can be found at many labs and CROs. This makes initial investment low and assay transfer and setup easy with limited need for training.
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